Development of microRNA-based TREATMENTS for MYOTONIC DYSTROPHY Type 1 by Translational Genomics Group

Dr. Artero working on rare diseases

Logo for TATAMI project aiming therapies against myotonic dystrophy

Dr. Artero’s Lab, based in Spain (University of Valencia), is a pioneer in discovering therapeutic targets and innovative drug candidates for rare diseases

VALENCIA, VALENCIA, SPAIN, February 28, 2021 /EINPresswire.com/ — Translational Genomics Group (Dr. Artero’s Lab), a Spanish research laboratory affiliated to the University of Valencia (UVEG) and INCLIVA Biomedical Research Institute, is a pioneer in discovering therapeutic targets and innovative drug candidates for rare diseases, has announced the development of novel DM1 (Myotonic Dystrophy Type 1) therapies based on recent new knowledge on microRNA class molecules. Being the most common muscular dystrophy in adults, affecting around 90,000 people in Europe and 75,000 in the US, the researchers from the Translational Genomics Group announced that their DM therapy could help these people and improve their quality of life.

About Myotonic Dystrophy Type 1

Myotonic dystrophy type 1 (DM1) is a life-threatening and chronically debilitating disease. The estimated incidence of the disorder worldwide is approximately one in 3,000-8,000 people, making it the most frequent adult muscular dystrophy. The disorder is inherited as an autosomal dominant trait, meaning that a child must inherit only one copy of the defective gene from one parent to develop the disease. Individuals born from individuals who are carriers of the mutated gene usually display age anticipation and higher severity for the clinical disease progression. Currently, there is no cure available to arrest or retard disease progression. Therefore, possible treatments are urgently needed since clinical management is limited to symptomatic care.

DM1 displays a wide range for onset of the clinical signs, including neonatal and infantile, to later adult forms being diagnosed. In a common clinical path, DM1 patients always manifest an important degree of progressive locomotor muscle weakness, atrophy, and myotonia, with the addition of less known, but also frequent, respiratory and cardiac impairments connected to other muscles degeneration, eventually leading to premature death, neurological issues causing social disabilities, and features outside the neuromuscular spectrum, including diabetes, cataracts, and higher cancer incidence.

Caused by an expansion of CTG repeats in a non-coding region of the DMPK gene, DM1 was the first disease ever described for which the underlying cause of the pathology involves an RNA-gain-of-function (RNA toxicity) mechanism. Upon transcription, expanded CUG in DMPK mRNAs form stable hairpin structures retained in the cell nucleus where they contribute to the abnormal binding and functional depletion of important factors strongly involved in RNA metabolism. Specifically, the limited availability of Muscleblind-like family factors (MBNLs) is the most significant contribution to DM1 phenotypes, like cardiac conduction problems, myotonia, and insulin resistance. However, the causes of other former critical clinical features in DM1 patients, like the significant muscular atrophy, are still not understood.

About Translational Genomics Group (Dr. Artero’s Lab):

Translational Genomics Group currently aims to identify therapeutic targets and develop innovative treatments for rare neuromuscular diseases (www.uv.es/gt). Very focused on DM1 from the very beginning, Dr. Artero and his team have provided the community with significant scientific advances that are now practical tools to push forward the development of novel drugs against DM1. Thus, their practical and rapid drug screening approaches have helped to identify and validate several chemical compounds, some licensed to the industry, for their further development in DM1. Dr. Artero´s long-term vision is highly relevant and transformative in filling in the gap between drug discovery and development in DM1 by leading the engagement of a multidisciplinary-driven effort to translate the results into actual treatments.

During the last years, Dr. Artero´s research has tracked to the DM1 field new actors to act together in a coordinated manner, intending to move novel candidate drugs to their next step. Research groups from top-notch European institutions such as Oxford University (UK) and CSIC (Spain), involved in medicinal chemistry of therapeutic oligonucleotides; Institute of Myology (France), developing novel animal model experimentation; IBEC (Spain), developing 3D tissue bioengineering; IIS Biodonostia (Spain), studying clinical evolution of the disease, are now directly involved in DM1 research through ongoing multidisciplinary projects like TATAMI (being funded by “la Caixa” Banking Foundation under the project code HR17-00268) or PROMETEO (being funded by regional Valencian Government) both coordinated by Dr. Artero. Significantly, non-scientific stakeholders are also involved in these projects to increase the chances of subsequent efforts, including national (ASEM Federation) and international (Myotonic Dystrophy Foundation) patient associations, research transfer offices, and regulatory CROs. At this moment, Dr. Artero is pursuing the construction of an European network for DM1 translational research with the incorporation of additional partners at scientific and non-scientific levels.

About microRNAs and DM1

In the last years, Dr. Artero’s group has pioneered the deciphering of small RNA regulatory molecules, called microRNAs (miRNAs), on distinct DM1 disease features.

By characterizing the miRNA-linked repression of the endogenous MBNL genes as an overlaid layer of regulation to the MBNL depletion pathway, they found two specific miRNAs (miR-23b and miR-218) that repress the expression of MBNL1 and MBNL2. Thus, the group has designed antisense oligonucleotides (AONs) that block the repressive miRNAs (antagomiRs), which have provided proof-of-concept to improve DM1-like alterations in a mouse model of the disease. Importantly, these results, under patent protection and recently published in the journal Nature Communications, led the creation, at the end of 2019, of a spin-off company of the University of Valencia, ARTHEx Biotech (www.arthexbiotech.com), that rapidly grown the interest of private investors at the bio & health field, completing an initial seed-round of 8M $ for the optimization of the drug candidate, subsequent preclinical regulatory studies, and design of the first clinical trial.

In a parallel research line, Dr. Artero´s group has recently published in Molecular Therapy Nucleic Acids how miR-7 contributes to the muscle atrophy phenotype in DM1 by studying its consequences replenishing or blocking miR-7 by using specific agomiR and antagomiR oligonucleotide molecules, respectively. Importantly, they highlighted that miR-7 dysfunction was linked to the alteration of catabolic muscle processes through autophagy- and atrophy-related pathways and support that restoration of miR-7 levels is a candidate therapeutic target counteracting muscle atrophy in DM1. A broader characterization of the molecular pathway for DM1 muscle atrophy is currently ongoing.

Want to crowdfund us? Contact at mecenzago@incliva.es
Want to collaborate with us? Contact at ruben.artero@uv.es

Rubén Artero Allepuz
Universidad de Valencia (SPAIN)
email us here

TATAMI research project: Trying to win the fight against Myotonic Dystrophy Type 1


Source: EIN Presswire

USA Merchants Targeting YoReSpot

YoReSpot

YoReSpot

Brandon Irlbeck (CEO YoReSpot)

Brandon Irlbeck (CEO YoReSpot)

BAYARD, IOWA, UNITED STATES, February 27, 2021 /EINPresswire.com/ —
There’s a new social media that is making waves with people from all over and with all backgrounds. The site is called YoReSpot. Created and funded by Brandon Irlbeck of Bayard, Iowa, this site was started with the belief that all people can come together without anyone experiencing the widespread censorship that other sites enforce. Whether it’s for a meme that you post, a comment made to someone, or even for liking things too much, too fast; this censorship has gotten out of hand, and it is only furthering the divide between people. YoReSpot has many features for it’s users to enjoy, including going live, calling in messenger, games, blog section and so much more. Not only does it have a familiar feel, but it runs smooth and the peaceful community like feel is astounding. A site for unity, for peaceful interactions, no matter what your spiritual beliefs, political or personal views are.

Despite standing up for unity, this site has not been met by everyone with open arms, including some other companies. In November of 2020, YoReSpot decided to use PayPal, Inc. for a one time payment of $9.99 for an ad-free version of the social networking site. This option removes ads, and also helps support the independently owned company. After just one week of use, PayPal emailed Irlbeck, CEO of YoReSpot, to inform him they were permanently suspending his business account. PayPal emails stated they did not have to explain why or how they came to this decision of action. Naturally, wanting to know why, a phone call took place between Irlbeck and PayPal in December of 2020. The PayPal representative stated that the company didn’t want anything to do with a site promoting Save the Children and Fund Homeless Vets movements, then proceeded to hang up on Irlbeck. They have since refused to engage in further contact with Irlbeck or his team and are still holding the money. “PayPal put a hold on a pretty decent chunk of change and said they would not release it for 180 days,” Irlbeck states, “none of this makes any sense to me. We haven’t done anything against their Terms of Service.”

Following the PayPal incident, Irlbeck decided to switch to Stripe for monetizing. Stripe was founded by John and Patrick Collison, with Patrick as the CEO. Things went very smooth with Stripe for a couple months, and Irlbeck thought that those issues were all in the past. Then on 2/26/2021, Stripe emailed Irlbeck saying they have permanently canceled the account and are holding the funds for 120 days. When Irlbeck tried to get an explanation, he got the familiar response that Stripe has the right to refuse to explain why his account was suspended permanently. “Here’s the kicker though,” Irlbeck says, “Stripe will not even allow me to refund users, they have locked my account completely.” So, Stripe is not just holding the money, but refusing to allow refunds as well; they’re effectively taking control of money that isn’t legally theirs, without a word of why or any communication thereafter.

Irlbeck has emailed his team of lawyers and is waiting back to find out if YoReSpot can take any legal action. “They have already gone through every transaction,” Irlbeck states, “and have concluded that neither PayPal or Stripe’s Terms of Service were not violated, in any way.” Some of his users have asked if there is anything they can do, while others are even calling for a boycott of Stripe and PayPal, Inc. for this ludicrous action made against such a respected and hardworking businessman. Irlbeck has vowed to do his best to find a payment company that does not have these policies and won’t shut accounts down without just cause.

Brandon L Irlbeck
YoReSpot
+ 16417450003
email us here


Source: EIN Presswire

WGP Global to Become the Sole Strategic Advisor to DiManEx

WGP Global and DiManEx announce that they have formalised an agreement for WGP Global to become the sole Strategic Advisor to the Dutch company.

We couldn’t be happier that DiManEx have appointed WGP Global as their sole strategic advisors.”

— David Orchard, President and Co-Founder, WGP Global

LONDON, CENTRAL, ENGLAND, February 27, 2021 /EINPresswire.com/ — WGP Global and DiManEx announced today that they have formalised an agreement for WGP Global to become the sole Strategic Advisor to the Dutch company.

Headquartered in Utrecht, DiManEx is a world leader in the integration of digital manufacturing technologies, in particular 3D printing, in global supply chains workflow.

“We are thrilled to be able to appoint WGP Global as our sole Strategic Advisors. Their expert advice on all aspects of corporate strategy will ensure that we stay ahead of the competition,” DiManEx CEO, Tibor van Melsem Kocsis, noted.

“DiManEx offers an end-to-end platform that leverages sophisticated machine learning to help identify the right parts for on-demand manufacturing, using supply chain and technical data. The platform integrates with your workflow and helps you avoid hardware and tooling investments. We support the part design, conversion and quality control process, so you can collaborate with colleagues across departments. Once your design is approved, our platform automatically matches your order with the Additive Manufacturing partner that best matches your material specifications and needs. The end result? A part delivered where and when you need it. Hassle-free.”

President and co-founder of WGP Global, specialists in all aspects of business, law and finance, David Orchard, said: “We couldn’t be happier that DiManEx have appointed WGP Global as their sole strategic advisors. As part of our service, we will be working alongside Tibor and his team to offer them specific tailored advice, a robust marketing strategy and insight which will ensure that DiManEx are in the safest hands.

“It is, and has always been, WGP Global’s intention to build upon our success and deliver consistent results for our clients.”

WGP Global was conceived in 2009 to combine the founders’ expertise, experience and networks to create what has grown into the WGP Global of today; a multi-generational practice built on traditional values and integrity, complemented by a progressive, modern approach to doing business in a borderless world.

The company is represented by a team of Legal, Compliance and Regulatory experts, captains of industry, diplomats, academics and thought-leaders in geopolitics & international affairs across many industries and specialisms.

Christopher Orchard
WGP Global
7780 438917
email us here
Visit us on social media:
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Twitter
LinkedIn


Source: EIN Presswire

Hood2Height’s Tanisha Janison Shares Her Top Tips for Financial Freedom to Empower Women Across the United States

Hood2Heights helps people achieve financial freedom by teaching them that the more they learn, the more they earn.

CLEVELAND, OH, USA, February 27, 2021 /EINPresswire.com/ — After overcoming challenges and adversities and taking meaningful steps along her journey to financial freedom, Tanisha Janison, a CEO, Author, and Mindshift Coach is proud to share the innovative platform she created to offer inspiration, hope, and motivation to people, teaching them to never settle and to always strive to make a positive change in their lives.

To this end, Tanisha created Hood2Heights, a program that teaches women how to generate passive income, multiply their income pool, build wealth, and achieve financial freedom. Tanisha recognizes that financial education and empowerment go hand in hand and that when women are equipped with the right tools and resources, they can change their lives forever. The Hood2Heights program puts these resources right into people’s hands. Tanisha’s coaching expertise makes every program feel perfectly tailored to the individual user, an essential part of staying focused and to staying motivated to implement the changes learned through completing the program.

“If I can change the life of even just one person, I will know everything I have done was worth it,” says Tanisha Jamison, CEO, Author, and Mindshift Coach of Hood 2 Heights. “In these ever-changing times, now more than ever, women have to think beyond the scope of just today and make diligent plans for the future.”

Tanisha went from being a nanny at 19 years old to being a multiple business owner earning enough in passive income to support her whole household. This success did not come overnight and instead was the result of hard work, trial and error, and pure grit and perseverance. Participants of the Hood2Heights program have a leg up because they have the opportunity to learn from Tanisha’s victories and mistakes.

Hood2Height’s programs were designed and curated based on the idea that women can depend on themselves and no one else. For this reason, Hood2Heights programs teach women to think like millionaires, speak positivity into the universe, and step into their power and potential to say goodbye to their 9-5 and hello to a new future. For just $20 per month, users can participate in the program and take advantage of a wealth of online resources. “Over the years, I paid inordinate sums to access information like this,” says Tanisha. “My goal in creating this program is to make these resources more affordable and accessible so the widest array of people can take advantage of these lessons.”

Tanisha has published several books and guidebooks detailing her best tips for success including 10 Passive Income Streams, The Millionaire Mind Shift, and an entire series based around generating passive income in various ways. Tanisha is available to speak at self-help seminars worldwide. For more information, visit Tanisha’s website and follow her on Facebook and Instagram.

About Hood2Heights
Hood2Heights has a mission of empowering women to depend on themselves through the right education, conversations, and services to become financially successful. Tanisha Jamison founded Hood2Heights to provide the marketplace with education and information regarding the accumulation of wealth. Having lived in an impoverished neighborhood in Cleveland, Ohio, Jamison became an entrepreneur at 24. By the time she was 28, she had three successful businesses. As a wife and the mother of four, she continued to overcome doubt, struggle, and fear to grow her ventures and become her household’s breadwinner.

Tanisha Jamison – CEO/Author/Mindshift Coach
Hood2Heights
+1 440-201-2057
email us here


Source: EIN Presswire

Noah Taliferro Joins Netflix’s Dear White People for their Fourth and Final Season

The Rising Star Will Play the Role of Omar in the Series

LOS ANGELES, CA, UNITED STATES, February 27, 2021 /EINPresswire.com/ — Noah Taliferro will be appearing in Netflix’s “Dear White People” in their final season, as Omar.

Based on Justin Simien’s famous indie feature, Dear White People is set against the climate of a predominantly white Ivy League university where racial tensions mix just below the surface. The series follows a group of Winchester University’s students of color as they navigate a diverse landscape of social injustice, cultural bias, political correctness and activism in the millennial age.

The American Actor Noah Taliferro is a rising actor and producer from Los Angeles. From booking his first guest star role as Young Jebediah on Netflix’s Family Reunion in 2018, to booking another role on Netflix and the CW’s hit show “All-American,” as cocky cornerback Bo Lemming.

Phil Hughta
Trazza Media
email us here


Source: EIN Presswire

Private Investigator Directory – Swiss Security Solutions LLC is listed as compliant and insured corporation

Worldwide, Global and International Private Investigator Directory

Worldwide Private Investigator Directory

Swiss Security Solutions LLC is providing private, financial, legal and other investigations and intelligence for criminal, business and civil cases.

You see, but you do not observe. There is a difference. ”

— A.C.D.

ZüRICH ZH, ZüRICH ZH, SWITZERLAND, February 27, 2021 /EINPresswire.com/ — Private Investigator Directory (www.private-investigator-directory.com) is a worldwide, global and international directory of private investigator offices and detective agencies which implemented the business excellence, premier quality services and corporate liability insurance policy, and are privacy and data protection compliant. Private Investigator Directory lists Investigations Agencies and Private Investigator Offices and Corporations that specialize in all types of investigative work such as, asset tracing and asset recovery, background investigations, skip tracing, civil investigations, corporate and commercial investigations, domestic and matrimonial investigations, tracing missing persons, IT forensics, company checks and all other types of private detective and investigations work. There are no fees and no membership obligations to be registered in the Private Investigator Directory. The Special Committee of International Law Enforcement Officers is deciding once a year, are they going to publish the specific private investigator office or detective agency in the private investigator directory or not.

Swiss Security Solutions LLC is listed as compliant and insured corporation with implemented business excellence and premier quality services. On the Webpage "Find your Private Investigator" the Swiss Security Solutions LLC is listed among others. Swiss Security Solutions Head office is located in Zürich, Switzerland. They have 200 years of know-how, we are globally operating, and they are authorized by the security department of state. They were on the cases worth more than USD 3 Billion.

From video surveillance to undercover investigations, Swiss Security Solutions utilizes state-of-the-art technology to accomplish your specific objectives. Their resources include counter-measures, electronic surveillance technology and night-sight capabilities, as well as the latest interviewing and investigative innovations. No matter how difficult the assignment, our extensive resources will provide you with the best results. On the other side, their investigations are structured for cost-effectiveness.

Corporations regularly face a myriad of situations that require investigation and fact finding. Every day, in-house and outside investigators search the globe, collecting facts and evidence for multinational clients in global corporate investigations. The need to conduct internal investigations may also arise from the general duty of the employer and senior management to supervise and control employees and the internal processes within the organization. A thoughtful and carefully structured approach to investigations is essential. Properly executed, internal investigations help to determine (a) if the suspicion of fraud or other illegal activity has merit; (b) who is involved in the wrongdoing and to what degree; (c) what the appropriate internal and external responses should be (including the risks associated to inadequate responses); (d) how to minimize the civil, regulatory and criminal exposure of the corporation, including its decision-makers; (e) what preventive measures apply to preclude repetition of the activity in question; and (f) how to minimize reputational risks. In contrast, improperly executed internal investigations increase the corporation’s potential exposure and the corresponding risks to the management and board of directors.

On the other side, since Covid Crisis, the private persons, organizations and family offices as well as investors are faced with high-tech fraudsters and online fraud cases beginning with romance scams, online broker scams and online investment frauds.

Swiss Security Solutions LLC Team is always just a phone call or E-Mail / text message away. Their Management has a collective 70 years of industry experience and will suggest a case plan, case strategy and solution for you today!

Elena Göldi
Swiss Security Solutions LLC
+41 445866033
info@swiss-security-solutions.com
Visit us on social media:
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Global and Swiss Business and Private Investigations and Intelligence


Source: EIN Presswire

CEO of Your Home Sold Guaranteed Realty Reveals 5-Star Reviews is Secret to Agency’s Billion Dollar Success

I always instill in them that if they were to set up deals up to get a 5 Star Review from every client as opposed to stopping short of that at the commission check, they would get MORE commission checks. Every time we meet a client, we are doing a deal to

ROSEMEAD, CA, UNITED STATES OF AMERICA, February 27, 2021 /EINPresswire.com/ — The award-winning CEO of Your Home Sold Guaranteed Realty, Rudy Lira Kusuma, revealed today that the driving force behind the company’s success, including closing 1 billion dollars in deals during the pandemic and selling homes three time faster on average, is a laser focus on getting 5-star reviews, repeat clients and referrals.

Kusuma discussed the topic in a series of social media posts, noting that, “My approach to leadership at Your Home Sold Guaranteed Realty is to encourage our agents to act as if their reviews were currency. Imagine if, rather than commission checks, reviews were what we relied on to pay the bills. Would this make a difference in how you interact with your clients?”

“This way of thinking is actually the basis for our training system which is set up to teach a method of striving for 5-star reviews from every client.” he continued. “This is what has made the difference for us as an award-winning brokerage and is the real secret to why we were able to close 1 billion dollars in real estate deals even during a global pandemic.”

In addition to receiving multiple five-star reviews on Google and Zillow, the broker and his team regularly receive praise through video testimonials from their clients. Your Home Sold Guaranteed Realty operates with a system that allows for a different kind of second-mile service baked into deals from the moment agents meet face to face with clients.

“Our agents are held to a very high standard.” Continued Kusuma. “I always instill in them that if they were to set up deals up to get a 5 Star Review from every client as opposed to stopping short of that at the commission check, they would get MORE commission checks. Every time we meet a client, we are doing a deal to get a lifetime customer. Everything in our process is built to do that. It’s all part of the system that makes it possible for us to repeat success with every client.”

Your Home Sold Guaranteed Realty is always actively looking for agents of a high caliber to join their award-winning team. Since their start in 2007, Your Home Sold Guaranteed Realty has operated with a strict no cold calling, no door knocking, and no prospecting policy. Instead, they use a proven system to generate leads and ensure a culture of providing 5-star service to continually bring in 5-star reviews from clients.

Your Home Sold Guaranteed Realty recently held an online event to celebrate their best agents’ achievements, including agents who made lifechanging gains in their income since joining the Your Home Sold Guaranteed Realty team.

“What we offer our agents is truly different.” Said Rudy Lira Kusuma. “We are a high energy team that brings our best to every client interaction and every listing and sale. Our team is constantly growing and we welcome agents who are looking for a brokerage where they can be successful, take pride in their quality of service and be a part of an award-winning and high earning team.”

To become a Your Home Sold Guaranteed Realty agent, applicants should be driven, coachable and possess an excellent work ethic. If you are interested in becoming a part of YHSGR’s high performing team and participating in company advantages such as their proven systems for lead generation, visit their website to learn more and enlist as an agent today.

Learn more about Rudy Lira Kusuma and the Your Home Sold Guaranteed Realty team by visiting www.yourhomesoldguaranteed.com.

About the Company:
Your Home Sold Guaranteed Realty was founded with this vision: To Be the Best Place to Work, Buy, and Sell Real Estate! If you have the desire to buy or sell a home, or to build a multi-million-dollar real estate team, Rudy L. Kusuma will share his secrets. He offers cutting-edge lead generation technology, pro-business growth systems, exclusive listing marketing, and millionaire agent training.

About CEO Rudy Lira Kusuma:
In business since 2007, Rudy L. Kusuma and the Your Home Sold Guaranteed Realty team have sold more than 5,000 homes totaling over $1 billion in real estate transactions. A No. 1 best-selling author who has been featured on Brian Tracy’s TV Show “The Real Estate Office of The Future,” Kusuma is CEO of Your Home Sold Guaranteed Realty in California and has led the organization to success due to his cutting-edge lead generation technology, pro-business growth systems, exclusive listing marketing, and millionaire agent training. His company “Your Home Sold Guaranteed Realty” was the recipient of the 2019 Best of Small Business Awards and has been recognized by the Los Angeles Business Journal TOP 100 Fastest Growing Private Company 2017, 2018, 2019 and INC 5000 Fastest Growing Private Company in America 2016, 2017, 2018, 2019, and 2020.

Contact Information:
Rudy Lira Kusuma, California Real Estate Broker 01820322
Company: Your Home Sold Guaranteed Realty
Phone: 626-789-0159
Location: Agents throughout Southern California
Website: www.YourHomeSoldGuaranteed.com

RUDY LIRA KUSUMA
YOUR HOME SOLD GUARANTEED REALTY, INC.
+1 626-789-0159
email us here
Visit us on social media:
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Source: EIN Presswire

Crank Music Announces the Signing of Brooke Hogan

Crank Media

VANCOUVER, BC, CANADA, February 26, 2021 /EINPresswire.com/ — Crank Music a division of Crank Media Inc. (OTC: CRKM) ("Crank Media" or the "Company") is pleased to announce that it has signed TV star Brooke Hogan.

Crank Music, a division of Crank Media Inc, has signed Brooke Hogan, the daughter of WWE wrestling superstar Hulk Hogan, to a COUNTRY MUSIC recording contract. Brooke has been in the entertainment industry as a singer, reality TV star and actor. Her life and career were chronicled on VH1's "Hogan Knows Best" and spin-off "Brooke Knows Best," and she went on to star in several films.

"I have been working with Brooke over the past 6 months and I am amazed by Brooke's musical talent after hearing her music, we have signed her to our label Crank Music and she is a great addition to the label's already top-radio-charting artist roster," said Stephen Brown, CEO of Crank Media. The first single “Love People” is being released to all digital platforms and Radio on Monday March 1st, 2021.

About Crank Media Inc.
Crank Media Inc (OTC: CRKM) is a multifaceted media company based in Vancouver. The Crank Media team is extremely well-versed in a variety of media and content delivery platforms in Music, Film, TV and Virtual Reality and is fast becoming a top-tier global media company. www.crankmedia.com

This press release includes “forward looking statements” within the meaning of the “safe harbor” provisions of the United States Private Securities Litigation Reform Act of 1995. When used in this press release, the words “estimates,” “projected,” “expects,” “anticipates,” “forecasts,” “plans,” “intends,” “believes,” “seeks,” “may,” “will,” “should,” “future,” “propose” and variations of these words or similar expressions (or the negative versions of such words or expressions) are intended to identify forward-looking statements. These forward-looking statements are not guarantees of future performance, conditions or results, and involve a number of known and unknown risks, uncertainties, assumptions and other important factors, many of which are outside the control of us, that could cause actual results or outcomes to differ materially from those discussed in the forward-looking statements. Important factors, among others, that may affect actual results or outcomes include: our ability to execute on our business plan; our ability to retain key personnel; general economic and market conditions impacting demand for our products and services; adequacy of our funds for future operations; our future expenses, revenue and profitability; our ability to develop new products; our dependence on key suppliers, manufacturers and strategic partners; and industry trends and the competitive environment in which we operate. These and other risk factors are discussed in our reports filed with the Securities and Exchange Commission. We do not undertake any obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

Contact:
Stephen Brown
Crank Media Inc
sb@crankmedia.ca

Stephen Brown
Crank Media Inc
email us here


Source: EIN Presswire

ILT Celebrates 20 Year Milestone

Twenty years later we’re more confident and dedicated than ever”

— Will McGregor

SALT LAKE CITY, UTAH, UNITED STATES, February 26, 2021 /EINPresswire.com/ — Integrated Lending Technologies, LLC (ILT), an industry leader in lending and leasing software, has reached a historic milestone with its 20 year anniversary. Starting with the acquisition of Dealer Indirect Lending and Leasing System (DILLS™) in 2001, ILT broke new ground in automating the indirect lending process. In response to both the changing industry landscape and client demands for versatility and additional functionality, ILT launched the Allegro™ Lending Suite, a cloud based loan origination system with expanded lending and leasing capabilities for direct, indirect and lifestyle lending in 2017. In October 2019 ILT completed conversion of all users from the legacy DILLS™ system to the new Allegro™ Lending Suite.

Regarding this milestone, President and CEO Will McGregor, who has been with ILT since its inception, said, “When we released the first version of DILLS™ in 2001, using the Internet as a way to manage indirect lending was a new idea. But we were confident and determined to make DILLS™ the standard in innovation, flexibility and ease of use. Twenty years later we’re more confident and dedicated than ever to retaining our position as the industry leader by adding even more functionality and configurability to Allegro™ to meet the particular demands of every lending situation.”

In celebration of this achievement, ILT released a new logo to commemorate the company’s journey.

Peter Vehko
Integrated Lending Technologies
+1 801-581-9500
email us here


Source: EIN Presswire

AFFIRM Testing Platform 2020 MVP for BlackFin Group

BlackFin Group has released its 2020 performance report, which shows its AFFIRM testing platform contributed significantly to the company’s growth.

Having a robust testing platform ready to go made 2020 a very good year for our company.”

— Lloyd Booth, BlackFin Group CTO

LAGUNA HILLS, CA, USA, February 26, 2021 /EINPresswire.com/ — BlackFin Group, a management consulting firm serving the Mortgage Banking Industry, has released its 2020 performance report to internal stakeholders, which shows that the company’s AFFIRM testing platform was embraced by the industry in 2020, contributing significantly to the company’s growth. AFFIRM is a state-of-the-art, blended approach to testing that delivers a cost-effective, accurate and efficient software testing strategy.

“2020 was all about digital lending for many lenders, as they struggled to keep up with volume and consumer expectations,” said BlackFin Group CEO Keith Kemph. “We saw a lot of new technology implemented last year. Testing is always a critical element of this process. Few other IT activities can be as difficult to get right or as costly to get wrong. This was a great opportunity for BlackFin Group and our AFFIRM testing platform.”

New software implementations are complex initiatives. Success is dependent upon a good testing methodology, but manual testing is expensive and time-consuming. AFFIRM combines well designed manual testing with affordable automated testing to tailor testing processes to meet each organization’s unique business processes. AFFIRM leverage's state-of-the-art technology and BlackFin Group’s own testing best practices, which are built upon decades of software implementation experience.

Last year, BlackFin Group worked with banks, credit unions and independent mortgage banks on new implementations as well as software updates and patches to existing solutions.

“Our client engagements may vary from analysis, to advisory, or doing the heavy lifting to implement your business strategy or technology initiative,” said BlackFin Group Chief Operating Officer and CTO Lloyd Booth. “Having a robust testing platform ready to go made 2020 a very good year for our company.”

For more information about AFFIRM or any of BlackFin Group’s consulting services, visit the company online.

About BlackFin Group
BlackFin Group is a management consulting firm that specializes in training, application development, and consulting within the Mortgage Banking Industry. We are skilled in the successful execution of your firms’ critical initiatives by providing clients the best in resources that ensure project success. For more information, contact the company at (949) 326-5675, info@BlackFin-Group.com, or visit its website https://www.blackfin-group.com.

Rick Grant
RGA Public Relations
+1 570-497-1026
rick.grant@rga-pr.com
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Source: EIN Presswire